Venture fund Euro Venture, founded by co-owners of IC "Euroinvest" Andrei Berezin and Yuri Vasilyev, entered as a financial partner in the consortium, which will create a unique medical device for the treatment of cancer

Участниками консорциума стали петербургские ученые, медики и промышленники - СПбГЭТУ «ЛЭТИ», Клиническая больница № 122 им. Л.Г. Соколова и АО «Светлана-Рентген». Суть проекта, объединившего эти организации – создание медицинского прибора для терапевтического лечения онкологических заболеваний путем непосредственного воздействия пучка рентгеновского излучения на внутренние опухоли, а также облучения области послеоперационного удаления раковых опухолей.


Объем инвестиций вкладываемых фондом Euro Venture в первый раунд этого проекта составит до 10 млн рублей.


«Это относительно небольшой объем, поскольку сейчас проект находится на стадии НИОКР. В ближайший год будет создан опытный образец данного аппарата, который и будет проходить клинические испытания в Клинической больнице №122, - пояснил Андрей Березин. – Затем, после завершения всех испытаний и сертификации, к началу 2020 года станет ясно, как можно масштабировать данный проект и какова может быть доля наших дальнейших инвестиций».

Медицинские эксперты отмечают, что прямых аналогов у такого прибора пока нет не только в России, но и за рубежом. При этом, по их предварительным оценкам, не менее 200 The participants of the consortium were St. Petersburg scientists, physicians and industrialists - SPETEETU "LETI", Clinical Hospital No. 122 named after. L.G. Sokolova and JSC "Svetlana-Roentgen". The essence of the project that united these organizations is the creation of a medical device for the therapeutic treatment of oncological diseases by direct exposure of the x-ray beam to internal tumors, as well as irradiation of the area of ​​postoperative removal of cancerous tumors.


The volume of investments made by the Euro Venture fund in the first round of this project will amount to 10 million rubles.


"This is a relatively small amount, because now the project is at the stage of R & D. In the next year, a prototype of this device will be created, which will be clinically tested at Clinical Hospital No. 122, "Andrei Berezin explained. "Then, after completing all the tests and certification, by the beginning of 2020 it will become clear how the project can be scaled and what proportion of our further investments can be."

Medical experts note that there are no direct analogs to such a device, not only in Russia, but also abroad. At the same time, according to their preliminary estimates, at least 200 domestic medical institutions need such equipment. Taking into account the fact that the devices of this level and functional cost at least 10 million rubles, the all-Russian volume of demand for a future innovative device is estimated at an average of 2 billion rubles.

At the heart of the device's effectiveness is the intra-operative irradiation - that is, exposure to X-ray sources inserted into the body of the patient, allowing "oncological sterilization" of the operating field, to prevent the scattering of tumor cells and to significantly reduce the incidence of local tumor recurrence, while minimizing the impact on the surrounding organs.


"Among the methods of treatment of malignant (oncological) diseases, radiation therapy occupies one of the leading places. More than 70% of cancer patients, it is used as a method of independent treatment or as one of the components of complex treatment. At present, radiotherapy is the main and radical method of treating such malignant tumors as skin and mucous membrane cancer of the oral cavity, some tumors of the genital organs, and lymphogranulomatosis. The combined use of radiotherapy in conjunction with surgery and chemotherapy significantly improves the results of treatment for breast, rectum, esophagus, bones and lung cancer, "explains one of the device developers Nikolai Potrakhov, head of the Department of Electronic Devices and Devices" LETI "and the head of the company" Eltech-Med "(which will create a ready-made device).


According to the Chief Thoracic Surgeon of St. Petersburg, the head of the Center for Thoracic Surgery (thorax surgery) of KB No. 122 Vadim Pischka, the uniqueness of the future device lies in the fact that it can be used immediately during surgery - when, through a small incision on the patient's body, the surgeon can combine removal of the malignant tumors with gamma-therapy of surrounding tissues with the use of soft radiation. "Such irradiation, performed directly during the operation, can be controlled by the surgeon visually. In addition, the time will not be lost after the operation, during which potential tumor cells could be fixed on healthy tissues, to subsequently become points of growth of implantation metastases, "the doctor explains. The unique ability of X-rays to penetrate to a given depth in this case can be a method of additional treatment of malignant neoplasms of the thoracic and abdominal cavity.


"However, there are no devices for carrying out such irradiation to date in the world. First of all, because the corresponding narrow X-ray tubes have not been developed, "Vadim Pishchik continues. - And to date, only the physicists of St. Petersburg, specialists of LETI and Svetlana-Roentgen, own the unique technology of creating narrow X-ray tubes.


According to the director of Svetlana-Roentgen JSC Nikolai Kulikov, the tubes, which were not created by his company, are already used in foreign devices for contact X-ray therapy.

"At the same time, an instrument that could be inserted through a 1.5-2 cm incision into sterile human cavities for intraoperative X-ray therapy has not been created by anyone. And this is what we are creating now, "he said.


Unlike traditional tubes, with a target inside the vacuum balloon, this tube has a protruding type tungsten target removed from the balloon on a long and thin anode tube. The small diameter and length of the anodic tube with a casing of 16 and 203 mm, respectively, allow for the therapy of lung cancer through the intercostal puncture into the chest of the patient an anode and place the target of the X-ray tube at the required distance from the tumor. The tube itself, together with a high-voltage power supply, is located in one housing - a monoblock of the X-ray apparatus (Pic. 1)















Pic. 1

Explaining the interest of the venture fund established by him to this medical project, Andrei Berezin notes: "First of all, it is based on scientific and technical developments made at the enterprise that is part of the Svetlana holding company, whose shareholders are the structures of IK Euroinvest. And we always said that PJSC "Svetlana" due to the modernization carried out there from 2017 will continue its development and will become the basis for a modern cluster of electronic industry, whose products will be oriented to various sectors and medicine in particular.


I am also confident that successful development and mastering in the serial production of X-ray devices for intraoperative radiation therapy will open a new segment in the market of domestic medical equipment. And, with the appropriate state support, will allow them to enter this international market

But most importantly, I hope that this project will provide a solution to the socially significant and important humanitarian task - shortening the terms of rehabilitation, increasing survival and prolonging the life of cancer patients. "


According to the owls of the director of the venture fund Euro Venture Roman Romaniuk, the creation of a device for intraoperative irradiation is the first, but not the only, medical project the fund is interested in.


"We are currently reviewing three more projects, one of which is also based on the development of Svetlana and is also aimed at the diagnosis, prevention and treatment of oncological diseases through the combined effects of low-intensity x-rays and microwave radiation," Roman Romanyuk explains. - We expect that such a development plan will not only be in demand, but also well-scalable. In this regard, we are counting on cooperation with the Ministry of Health (which could act as a customer for existing and promising developments) and with other private and public entities where enterprises could mass produce domestic innovative equipment). "


As Roman Romanyuk specifies, now on the payline the fund has about ten projects with investment requirements from 15 to 60 million rubles each. They are mostly in the electronics field, but there are also new digital platforms, as well as projects in the field of automation of the agro-industry.


In addition to investing in directly innovative projects, the Foundation supports the development of young scientists and innovators in St. Petersburg and Leningrad region. Thus, in April 2018, Andrei Berezin established a personal scientific scholarship for students and post-graduate students of VOENMEKh, named after Georgy Grechko, an outstanding graduate of VOENMEKH, a cosmonaut, twice Hero of the Soviet Union. This semester was given to 18 students and post-graduate students, who made a significant contribution to the scientific and research work of the university.




Venture fund Euro Venture was established in May 2017 by Andrei Berezin and Yury Vasiliev (co-owners of IC "Euroinvest"). The initial volume of the Euro Venture fund is 10 million euros and the priority areas of investment are innovative developments in the scientific and technical sphere - first of all electronics, new materials and technology TechNet, as well as projects in the creative industry.


Additional Information

Alina Mamadshoeva, specialist of the external communications department of the fund Euro Venture

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